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KMID : 0384320060270121013
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Korean Journal of Family Medicine
2006 Volume.27 No. 12 p.1013 ~ p.1017
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Development of Liver Cirrhosis in a Elderly Healthy Hepatitis B Carrier with Rheumatoid Arthritis Treated with Low-dose Methotrexate (MTX)
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Kong Mi-Hee
Lee Tae-Young
Kim A-Ryon
Joo Nam-Seok
Kim Kwang-Min
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Abstract
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Methotrexate (MTX) is the most widely used slow-acting anti-rheumatic agent in the treatment of rheumatoid arthritis. But, long-term administration of MTX can be complicated with liver fibrosis and even cirrhosis. We report the case in elderly woman with healthy Hepatitis B viral carrier patient who developed liver cirrhosis without viral replication after low-dose MTX therapy for rheumatoid arthritis. (J Korean Acad Fam Med 2006;27: 1013-1017)
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KEYWORD
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HBV healthy carrier, elderly, rheumatoid arthritis, liver cirrhosis
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